ISEcp1-mediated transposition of qnrB-like gene in Escherichia coli.
نویسندگان
چکیده
A novel QnrB-like plasmid-mediated resistance determinant, QnrB19, was identified from an Escherichia coli clinical isolate from Colombia. Its gene was associated with an ISEcp1-like insertion element that did not act as a promoter for its expression. Using an in vitro model of transposition, we showed that the ISEcp1-like element was able to mobilize the qnrB19 gene.
منابع مشابه
ISEcp1-mediated transposition of linked blaCTX-M-3 and blaTEM-1b from the IncI1 plasmid pEK204 found in clinical isolates of Escherichia coli from Belfast, UK.
OBJECTIVES Linked bla(CTX-M-3)-bla(TEM-1b) genes, as found on the IncI1 plasmid pEK204 prevalent in Belfast, also occur on plasmids belonging to other rep types in Escherichia coli isolated from nursing-home residents in Belfast. We investigated the mechanisms for their joint dissemination among diverse plasmids. METHODS Plasmid pEK204 was transferred by electroporation into E. coli DH5α harb...
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ورودعنوان ژورنال:
- Antimicrobial agents and chemotherapy
دوره 52 8 شماره
صفحات -
تاریخ انتشار 2008